Director, Oncology Safety Toxicology

We are supporting a leading international biopharmaceutical organisation in the appointment of a Director of Oncology Safety Toxicology, a key leadership role within their non-clinical development function.

This position will be responsible for defining and driving preclinical safety strategy across a portfolio of innovative oncology programmes, including biologics and next-generation therapeutic modalities. The role offers strong visibility within global project teams and direct impact on candidate progression into clinical development.

Key Responsibilities

• Provide strategic oversight of non-clinical safety and toxicology activities for oncology assets
• Design and implement preclinical safety strategies, including safety pharmacology and immunotoxicology
• Lead the interpretation of toxicology data, delivering clear risk assessments to support decision-making
• Contribute to regulatory submissions (IND/CTA) and represent non-clinical safety in interactions with health authorities (EMA/FDA)
• Partner closely with discovery, translational, clinical, and regulatory teams in a matrix environment
• Lead and mentor scientists, fostering scientific excellence and collaboration

Candidate Profile

• PhD (or equivalent) in Toxicology, Pharmacology, Immunology, or a related discipline
• Extensive experience in preclinical safety/toxicology within the pharmaceutical or biotechnology industry
• Strong background in oncology drug development; experience with biologics or immuno-oncology is highly desirable
• In-depth knowledge of global regulatory requirements for non-clinical safety (EMA/FDA)
• Demonstrated leadership capabilities and experience influencing cross-functional teams
• Excellent communication skills, with experience contributing to regulatory documentation