Key Considerations When Hiring a Principal Investigator (PI)
24 July, 2025
Summary
COPD, Asthma PI High-Level CM Model
Key Considerations When Hiring a Principal Investigator (PI)
Financial Appeal is Critical: PIs must clearly see the potential for incremental earnings through site or network participation.
Transparent Economics: Leadership should clearly outline expected hours per study and potential study volume to justify the opportunity.
The Chicken & Egg Challenge: Many sponsors hesitate to hire a PI without first securing a contract, yet need a PI in place to win studies.
Barrington James Insight:
- Start with a contractual retainer model—engage the PI on an hourly basis as trials begin.
- Transition to a full-time hire once study volume justifies the investment.
- Download a sample financial model to guide your approach